SCHEMBL28436716

SCHEMBL28436716

COC(=O)C12CCN(CC1)CC2

nearest known ligand 0.76

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
CHRM1 P11229 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM3 P20309 1/20 0.35
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3318136 0.86 CHRM2 (0.44) HSD11B1NPSR1CHRM1CHRM2CHRM4
SCHEMBL2445606 0.82 NPSR1 (0.46) HSD11B1NPSR1CHRM1LMNAMEN1
Oxalic Acid SCHEMBL9051874 0.81 CHRM1 (0.41) HSD11B1NPSR1CHRM1CHRM2CHRM4
SCHEMBL9050441 0.80 CHRM2 (0.50) HSD11B1NPSR1CHRM1CHRM2CHRM4
SCHEMBL3220818 0.76 OPRM1 (0.41) MEN1KMT2A
Oxalic Acid SCHEMBL9049463 0.76 CHRM2 (0.47) HSD11B1NPSR1CHRM1CHRM2CHRM4
SCHEMBL2451039 0.75 NPSR1 (0.46) HSD11B1NPSR1CHRM1LMNAMEN1
Bromide SCHEMBL30309841 0.74 OPRM1 (0.41) MEN1KMT2A
Hydrochloric Acid SCHEMBL29435164 0.74 OPRM1 (0.43)
SCHEMBL8790010 0.74 CHRM2 (0.41) HSD11B1NPSR1CHRM1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111484445-B Method for separating and purifying intermediate of high-purity Wumei ammonium bromide 广东莱佛士制药技术有限公司 2021-05-18 CN disclosed
CN-111484445-A Method for synthesizing intermediate of high-purity Wumei ammonium bromide 广东莱佛士制药技术有限公司 2020-08-04 CN disclosed