Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011114 | 0.84 | MEN1 (0.34) | MAPTMEN1KMT2APKMALDH1A1 | |
| SCHEMBL28696640 | 0.76 | RPS6KB2 (0.35) | KDM4EMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL21702363 | 0.73 | SMN1; SMN2 (0.31) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28399995 | 0.72 | MAPT (0.32) | KDM4EMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL5247017 | 0.72 | ACLY (0.48) | ACLYMAPTHIF1ATSHRMEN1 | |
| SCHEMBL2139894 | 0.71 | LMNA (0.42) | MAPTALDH1A1LMNAHTTCYP2C9 | |
| SCHEMBL28897264 | 0.71 | GRM5 (0.35) | KDM4EMAPTL3MBTL1DHFRCYP2C9 | |
| SCHEMBL20630830 | 0.69 | KMT2A (0.36) | KDM4EMAPTHIF1AHSD17B10MEN1 | |
| SCHEMBL20630123 | 0.69 | TXNRD1 (0.33) | KDM4EMAPTHIF1AHSD17B10SMN1; SMN2 | |
| SCHEMBL21637594 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116513-B | Fixed-point bromination method of 2,1, 3-benzothiadiazole derivative | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-111116513-A | Fixed-point bromination method of 2,1, 3-benzothiadiazole derivative | 浙江工业大学 | 2020-05-08 | — | — | CN | disclosed |