SCHEMBL21702363

SCHEMBL21702363

Fc1cc2nsnc2c(-c2cc3c(ccc4nsnc43)c3nsnc23)c1F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28437243 0.73 ACLY (0.39) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL12170102 0.71 MAPT (0.50) MEN1MAPTKMT2A
SCHEMBL29011114 0.71 MEN1 (0.34) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL28696640 0.67 RPS6KB2 (0.35) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL20630123 0.67 TXNRD1 (0.33) SMN1; SMN2MAPT
SCHEMBL28399995 0.66 MAPT (0.32) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL9940784 0.64 MAPT (0.44) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL20630830 0.63 KMT2A (0.36) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL26201427 0.63 KDM4E (0.34) SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL21637594 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11031557-B2 Conjugated polymers based on terthiophene and their applications RAYNERGY TEK INC. (TW) 2021-06-08 US disclosed
US-20200052217-A1 CONJUGATED POLYMERS BASED ON TERTHIOPHENE AND THEIR APPLICATIONS RAYNERGY TEK INC. (TW) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052217-A1 CONJUGATED POLYMERS BASED ON TERTHIOPHENE AND THEIR APPLICATIONS TERT, TTI2, TTI1 SMN1; SMN2 1149/4885MEN1 4399/4885MAPT 31/4885
US-11031557-B2 Conjugated polymers based on terthiophene and their applications TERT, TTI2, TTI1 SMN1; SMN2 1149/4885MEN1 4399/4885MAPT 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.