Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC1 | P48995 | 1/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | XPA | P23025 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44446 | 0.92 | ALDH1A1 (0.38) | NOTUMTDP1CTSBALDH1A1POLB | |
| SCHEMBL4897613 | 0.92 | ALDH1A1 (0.38) | NOTUMTDP1CTSBALDH1A1POLB | |
| SCHEMBL6553961 | 0.87 | LMNA (0.36) | NOTUMTDP1CTSBALDH1A1POLB | |
| Clopyralid SCHEMBL7586754 | 0.87 | NOTUM (0.35) | TRPC1TRPC3STIM1ORAI1NOTUM | |
| SCHEMBL2961429 | 0.86 | TDP1 (0.36) | NOTUMTDP1CTSBALDH1A1POLB | |
| SCHEMBL2964906 | 0.86 | TDP1 (0.36) | NOTUMTDP1CTSBALDH1A1POLB | |
| SCHEMBL9350408 | 0.84 | TDP1 (0.35) | NOTUMTDP1CTSBALDH1A1POLB | |
| SCHEMBL7953670 | 0.84 | KMT2A (0.37) | NOTUMTDP1CTSBRORCALDH1A1 | |
| SCHEMBL2968009 | 0.84 | LMNA (0.36) | NOTUMTDP1CTSBALDH1A1POLB | |
| SCHEMBL2966447 | 0.84 | LMNA (0.36) | NOTUMTDP1CTSBALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874967-A | Composition, polymer composite article formed therewith, and method of making the same | 美国陶氏有机硅公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-111433275-B | Composition, polymer composite article formed therewith, and method of making the same | 美国陶氏有机硅公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111630103-B | Composition, polymer composite article formed therewith, and method of making same | 美国陶氏有机硅公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-111630103-A | Composition, polymer composite article formed therewith, and method of making same | 美国陶氏有机硅公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111433275-A | Composition, polymer composite article formed therewith, and method of making same | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | disclosed |