Clopyralid

Clopyralid

SCHEMBL7586754

CC(C)OC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl.O=C(O)c1nc(Cl)ccc1Cl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 3/20 0.35
TDP1 Q9NUW8 3/20 0.34
CTSB P07858 1/20 0.34
ALDH1A1 P00352 4/20 0.34
THRB P10828 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
POLB P06746 3/20 0.32
LMNA P02545 1/20 0.32
CASP6 P55212 2/20 0.32
CTDSP1 Q9GZU7 2/20 0.32
NSD2 O96028 1/20 0.32
PKM P14618 1/20 0.32
APEX1 P27695 1/20 0.32
CASP3 P42574 1/20 0.32
RECQL P46063 1/20 0.32
XPA P23025 1/20 0.32
MAPT P10636 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
TRPC1 P48995 1/20 0.32
TRPC3 Q13507 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897613 0.90 ALDH1A1 (0.38) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL44446 0.90 ALDH1A1 (0.38) NOTUMTDP1CTSBALDH1A1THRB
Benzoic Acid SCHEMBL28437397 0.87 TRPC1 (0.37) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL6553961 0.85 LMNA (0.36) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL2961429 0.84 TDP1 (0.36) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL2964906 0.84 TDP1 (0.36) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL9350408 0.82 TDP1 (0.35) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL7953670 0.82 KMT2A (0.37) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL2968009 0.82 LMNA (0.36) NOTUMTDP1CTSBALDH1A1THRB
SCHEMBL2966447 0.82 LMNA (0.36) NOTUMTDP1CTSBALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT NOTUM 60/4885TDP1 1969/4885CTSB 1242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.