Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 known ✓ | P04062 | 1/20 | 0.34 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.31 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1357296 | 0.85 | CAMK2A (0.39) | OR51E2LMNAALDH1A1PTPN1CAMK2A | |
| Lactic Acid SCHEMBL3674424 | 0.84 | TP53 (0.48) | PDE4AOR51E2LMNAALDH1A1PTPN1 | |
| Oxalic Acid SCHEMBL28437633 | 0.83 | CAMK2A (0.38) | OR51E2LMNAALDH1A1PTPN1CAMK2A | |
| SCHEMBL11357862 | 0.82 | ALDH1A1 (0.38) | OR51E2LMNAALDH1A1CAMK2ACHRM1 | |
| Acetic Acid SCHEMBL3683183 | 0.81 | ALDH1A1 (0.41) | OR51E2LMNAALDH1A1PTPN1CAMK2A | |
| Carbamic Acid SCHEMBL1073227 | 0.81 | CAMK2A (0.36) | OR51E2LMNAALDH1A1PTPN1CAMK2A | |
| Glycolic Acid SCHEMBL11515132 | 0.81 | CAMK2A (0.42) | OR51E2LMNAALDH1A1PTPN1CAMK2A | |
| Acetic Acid SCHEMBL540581 | 0.81 | ALDH1A1 (0.41) | OR51E2LMNAALDH1A1PTPN1CAMK2A | |
| SCHEMBL15027 | 0.80 | — | — | |
| Malic Acid SCHEMBL28058264 | 0.79 | SMN1; SMN2 (0.58) | OR51E2PTPN1CAMK2AGPR84TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631779-B | Polyol esters and their use in processing halogenated vinyl polymers | 济南金昌树新材料科技有限公司 | 2020-07-14 | — | — | CN | disclosed |