Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443611 | 0.80 | MGAM (0.61) | RAB9ANPC1ALDH1A1KDM4EMGAM | |
| SCHEMBL6434016 | 0.76 | KDM4E (0.49) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28605670 | 0.74 | CNR2 (0.62) | RAB9ANPC1ALDH1A1KDM4EMGAM | |
| SCHEMBL22501419 | 0.73 | RAB9A (0.50) | RAB9ANPC1ALDH1A1KDM4EMGAM | |
| SCHEMBL565974 | 0.72 | CES2 (0.64) | RAB9ANPC1ALDH1A1KDM4EKMT2A | |
| SCHEMBL12256867 | 0.71 | MGAM (0.64) | RAB9ANPC1ALDH1A1KDM4EMGAM | |
| SCHEMBL5873384 | 0.70 | CES2 (0.61) | RAB9ANPC1ALDH1A1KDM4EKMT2A | |
| SCHEMBL4196929 | 0.70 | CES2 (0.61) | RAB9ANPC1ALDH1A1KDM4EKMT2A | |
| Ethylene SCHEMBL28075502 | 0.70 | CES2 (0.61) | RAB9ANPC1ALDH1A1KDM4EKMT2A | |
| SCHEMBL22501398 | 0.70 | KDM4E (0.66) | RAB9ANPC1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111494381-B | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-111494381-A | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2020-08-07 | — | — | CN | disclosed |