Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605670 | 0.87 | CNR2 (0.62) | RAB9ANPC1CNR2MGAMCYP1A2 | |
| SCHEMBL28443611 | 0.83 | MGAM (0.61) | RAB9ANPC1CNR2MGAMCYP1A2 | |
| SCHEMBL11316978 | 0.78 | CNR2 (0.69) | RAB9ANPC1CNR2MGAMCYP1A2 | |
| SCHEMBL22501398 | 0.76 | KDM4E (0.66) | RAB9ANPC1CNR2MGAMKDM4E | |
| SCHEMBL3860500 | 0.76 | HSD17B14 (0.52) | RAB9ANPC1CNR2MGAMHDAC6 | |
| SCHEMBL8746411 | 0.74 | CNR2 (0.47) | RAB9ANPC1CNR2MGAMKDM4E | |
| SCHEMBL27828157 | 0.74 | CNR2 (0.44) | RAB9ACNR2MGAMKDM4EHDAC8 | |
| SCHEMBL12256867 | 0.74 | MGAM (0.64) | RAB9ANPC1CNR2MGAMCYP1A2 | |
| SCHEMBL2480615 | 0.73 | MGAM (0.50) | RAB9ANPC1CNR2MGAMCYP1A2 | |
| SCHEMBL28437810 | 0.73 | RAB9A (0.46) | RAB9ANPC1CNR2MGAMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479803-B2 | Antimalarial compounds | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2022-06-30 | — | — | US | disclosed |
| WO-2020206252-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479803-B2 | Antimalarial compounds | H1-3, FPR3, NHERF1 | RAB9A 1335/4885NPC1 51/4885CNR2 987/4885 |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | H1-3, FPR3, NHERF1 | RAB9A 1335/4885NPC1 51/4885CNR2 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.