Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443611 | 0.87 | MGAM (0.61) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1408599 | 0.81 | CES2 (0.58) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL13475582 | 0.79 | KDM4E (1.00) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| Methyl Alcohol SCHEMBL28478481 | 0.79 | ALDH1A1 (0.58) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28605670 | 0.77 | CNR2 (0.62) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6430262 | 0.76 | KDM4E (0.50) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL22501419 | 0.76 | RAB9A (0.50) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| Quinoline SCHEMBL28307189 | 0.75 | ALDH1A1 (0.57) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL12256867 | 0.74 | MGAM (0.64) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3162890 | 0.72 | SMN1; SMN2 (0.52) | KDM4ERAB9AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479803-B2 | Antimalarial compounds | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| CN-111494381-B | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2023-07-28 | — | — | CN | disclosed |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2022-06-30 | — | — | US | disclosed |
| WO-2020206252-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| CN-111494381-A | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2020-08-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479803-B2 | Antimalarial compounds | H1-3, FPR3, NHERF1 | KDM4E 3559/4885RAB9A 1335/4885ALDH1A1 3012/4885 |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | H1-3, FPR3, NHERF1 | KDM4E 3559/4885RAB9A 1335/4885ALDH1A1 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.