Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28446861 | 0.96 | LMNA (0.31) | LMNATHRBHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28019190 | 0.79 | — | — | |
| SCHEMBL13822426 | 0.77 | — | — | |
| Bromide SCHEMBL28377463 | 0.76 | ALDH1A1 (0.30) | LMNA | |
| SCHEMBL6791484 | 0.74 | — | — | |
| SCHEMBL28896401 | 0.71 | — | — | |
| Sulfuric Acid SCHEMBL28435461 | 0.71 | — | — | |
| SCHEMBL27897182 | 0.71 | — | — | |
| Sulfuric Acid SCHEMBL28435462 | 0.70 | — | — | |
| SCHEMBL28072435 | 0.70 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110252407-B | Method for preparing core-shell structure catalyst by carboxyl functionalized ionic liquid | 福州大学 | 2020-08-11 | — | — | CN | disclosed |