SCHEMBL28438470

SCHEMBL28438470

Cc1cc(C(=O)O)c(Cl)c(OCC(F)(F)F)c1S(C)(=O)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.38
ALDH1A1 P00352 4/20 0.35
LMNA P02545 3/20 0.35
NOTUM Q6P988 1/20 0.35
MAPK1 P28482 1/20 0.35
ACLY P53396 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
MRGPRX1 Q96LB2 2/20 0.32
RECQL P46063 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
RXRA P19793 2/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
HNF4A P41235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28442729 0.90 SCN9A (0.38) SCN9AALDH1A1LMNAMAPK1CYP1A2
SCHEMBL28747609 0.88 SCN9A (0.39) SCN9AALDH1A1LMNACYP1A2CYP3A4
SCHEMBL8492178 0.77 LMNA (0.41) ALDH1A1LMNANOTUMACLYMEN1
SCHEMBL29113488 0.76 LMNA (0.35) ALDH1A1LMNAMAPK1HPGD
SCHEMBL10571779 0.71 LMNA (0.38) ALDH1A1LMNAMAPK1ACLYCYP3A4
SCHEMBL28557666 0.71 CYP1A2 (0.41) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL9040944 0.69 PLAU (0.43) ACLYKMT2ARXRAMRGPRX4HNF4A
SCHEMBL28550673 0.69 ACLY (0.36) ALDH1A1LMNAMAPK1ACLYCYP1A2
SCHEMBL2825364 0.66 SLC6A9 (0.51) ALDH1A1LMNACYP1A2CYP3A4CYP2D6
SCHEMBL29253906 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440099-B Purification method of tembotrione product 利民化学有限责任公司 2022-01-04 CN disclosed
CN-112645853-A Preparation method of 2-chloro-3-alkoxymethyl-4-methylsulfonylbenzoic acid 江西天宇化工有限公司 2021-04-13 CN disclosed
CN-111440099-A Purification method of tembotrione product 利民化学有限责任公司 2020-07-24 CN disclosed