Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9436652 | 0.82 | SLC9A1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL9436646 | 0.81 | ALDH1A1 (0.37) | ACLYHTTCNR2KMT2A | |
| SCHEMBL16759783 | 0.75 | L3MBTL1 (0.49) | L3MBTL1MRGPRX4CNR2RXRAHNF4A | |
| SCHEMBL9043010 | 0.73 | KDM4E (0.47) | PLAUTPMTACLYTTR | |
| SCHEMBL11844723 | 0.72 | L3MBTL1 (0.40) | PLAUALOX15HTTL3MBTL1KMT2A | |
| SCHEMBL9038640 | 0.72 | TTR (0.48) | TPMTACLYPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL8492178 | 0.71 | LMNA (0.41) | ACLYALOX15HTTL3MBTL1MRGPRX4 | |
| SCHEMBL9042697 | 0.70 | TTR (0.47) | PLAUTPMTACLYPOLBKMT2A | |
| SCHEMBL31401376 | 0.70 | TTR (0.47) | TPMTACLYPOLBL3MBTL1KMT2A | |
| SCHEMBL8161835 | 0.70 | L3MBTL1 (0.49) | TPMTPOLBALOX15HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556674-B1 | 3,5-substituted benzoylguanidines with antiarrhythmic activity and cell proliferation inhibiting activity | HOECHST AG (DE) | 1996-06-19 | — | — | EP | disclosed |
| US-5373024-A | 3,5-Substituted benzoylguanidines, process for their preparation, their use as a medicament of diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-13 | — | — | US | disclosed |
| EP-0556674-A1 | 3,5-substituted benzoylguanidines with antiarrhythmic activity and cell proliferation inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |