SCHEMBL22654069

SCHEMBL22654069

Cc1nn(C)c(=O)c(-c2c(F)ccc(Cl)c2/C=C/c2ccc(C3CC3)cc2)c1OC(=O)C(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.31
PROKR1 Q8TCW9 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22031795 0.90 P2RX7 (0.33)
(Z)-1,2-Diphenylethene SCHEMBL29582372 0.87 TP53 (0.33)
SCHEMBL29658200 0.86 P4HB (0.31)
SCHEMBL27200156 0.86 P4HB (0.31)
SCHEMBL29216939 0.83 CCR2 (0.31) FPR2PROKR1MGLL
SCHEMBL22906296 0.83 MAPT (0.36)
SCHEMBL24661366 0.83 KEAP1 (0.30)
SCHEMBL30424370 0.83 PTGES (0.33)
SCHEMBL22031783 0.83 PTGES (0.33)
SCHEMBL24661317 0.82 P2RX3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4371986-B1 SUBSTITUTED PYRIDAZINONES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP disclosed
US-12540120-B2 Herbicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2026-02-03 US disclosed
CN-114555563-B Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-11-15 CN disclosed
EP-3999494-B1 SUBSTITUTED PYRIDAZINONES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2024-09-11 EP disclosed
CN-118108674-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-31 CN disclosed
CN-118084803-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN disclosed
CN-118084802-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN disclosed
EP-4371986-A2 SUBSTITUTED PYRIDAZINONES AS HERBICIDES Syngenta Crop Protection AG (CH) 2024-05-22 EP disclosed
EP-4357344-A2 SUBSTITUTED PYRIDAZINONES AS HERBICIDES Syngenta Crop Protection AG (CH) 2024-04-24 EP disclosed
EP-3737667-B1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2024-04-03 EP disclosed
CN-111566094-B herbicidal compounds 先正达参股股份有限公司 2023-10-13 CN disclosed
US-20220281827-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-09-08 US disclosed
CN-114555563-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2022-05-27 CN disclosed
EP-3999494-A2 SUBSTITUTED PYRIDAZINONES AS HERBICIDES Syngenta Crop Protection AG (CH) 2022-05-25 EP disclosed
WO-2021009334-A2 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-01-21 WO disclosed
WO-2021009334-A2 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-01-21 WO disclosed
US-20210009530-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-01-14 US disclosed
US-20210009530-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-01-14 US disclosed
EP-3737667-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-11-18 EP disclosed
CN-111566094-A Herbicidal compounds 先正达参股股份有限公司 2020-08-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009530-A1 HERBICIDAL COMPOUNDS DDT, HPD, PGD FPR2 4429/4885PROKR1 4492/4885MGLL 898/4885
US-20220281827-A1 HERBICIDAL COMPOUNDS DDT, HPD, PGD FPR2 4429/4885PROKR1 4492/4885MGLL 898/4885
US-12540120-B2 Herbicidal compounds CBR3, CBR1, HACL2 FPR2 4383/4885PROKR1 3984/4885MGLL 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.