Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 3/20 | 0.44 |
| ▸ | P4HB | P07237 | 11/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849631 | 0.83 | KCNH2 (0.42) | P4HBMAPTKDM4DKCNH2PTGS1 | |
| SCHEMBL2849965 | 0.70 | KDM4D (0.45) | SMAD3P4HBMAPTKDM4DKCNH2 | |
| SCHEMBL16225988 | 0.69 | ACHE (0.51) | MAPTKCNH2PTGS1PTGS2PSEN1 | |
| SCHEMBL1121365 | 0.68 | CYP4F2 (0.39) | MIF | |
| SCHEMBL1121430 | 0.67 | IDO1 (0.50) | MAPTMEN1KMT2A | |
| SCHEMBL2844400 | 0.67 | KCNH2 (0.72) | P4HBMAPTKCNH2PTGS1PTGS2 | |
| SCHEMBL31076387 | 0.66 | USP2 (0.42) | MAPTMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL2842842 | 0.66 | P4HB (0.54) | SMAD3P4HBALDH1A1 | |
| SCHEMBL31076389 | 0.66 | ALDH1A1 (0.36) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31371309 | 0.64 | CYP4F2 (0.40) | PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |