SCHEMBL31076387

SCHEMBL31076387

CC1CCN(c2ccc(CO[Si](C)(C)C(C)(C)C)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.42
RAB9A P51151 5/20 0.40
NPC1 O15118 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MCL1 Q07820 1/20 0.39
GAA P10253 3/20 0.36
MAPT P10636 3/20 0.36
POLB P06746 2/20 0.36
MAPK1 P28482 2/20 0.36
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HRH3 Q9Y5N1 3/20 0.36
USP14 P54578 1/20 0.36
MEN1 O00255 1/20 0.36
PKM P14618 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17025326 0.85 ALOX5AP (0.35) L3MBTL1HRH3USP14CYP3A4ALOX5AP
SCHEMBL31076389 0.80 ALDH1A1 (0.36) USP2RAB9ANPC1SMN1; SMN2GAA
SCHEMBL31073006 0.78 HRH3 (0.38) HRH3TSHR
SCHEMBL31073392 0.78 CKS1B (0.46) L3MBTL1USP14KMT2ADDB1CRBN
SCHEMBL31073086 0.78 TRPC6 (0.36)
SCHEMBL31076361 0.77 SMN1; SMN2 (0.40) USP2RAB9ANPC1SMN1; SMN2MCL1
SCHEMBL30555355 0.77 USP14 (0.41) GAAMAPTMAPK1ALDH1A1L3MBTL1
SCHEMBL31073262 0.76 HRH3 (0.36) SMN1; SMN2MAPTHRH3TSHR
SCHEMBL31073153 0.75 DHFR (0.34)
SCHEMBL23355718 0.75 RORC (0.36) RAB9AALDH1A1L3MBTL1KDM4EHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642778-A1 LSD1 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-11-05 EP disclosed
WO-2024141757-A1 LSD1 MODULATORS EXSCIENTIA AI LIMITED (GB) 2024-07-04 WO disclosed