Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508381 | 0.72 | KMT2A (0.49) | KMT2AMEN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL4271628 | 0.69 | TPMT (0.47) | KMT2AMEN1MAPTACLYTDP1 | |
| SCHEMBL1307525 | 0.68 | DHODH (0.74) | KMT2AMEN1KCNK2KCNK10MAPT | |
| SCHEMBL3712805 | 0.68 | PTPN11 (0.66) | KMT2AMEN1POLBMAPTERO1A | |
| SCHEMBL28445001 | 0.68 | HSP90AA1 (0.50) | KMT2AMEN1MAPTSMN1; SMN2HDAC2 | |
| SCHEMBL1491944 | 0.67 | ALDH1A1 (0.54) | KMT2AMEN1MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL17166275 | 0.66 | AKR1C2 (0.73) | KMT2AMEN1POLBKCNK2KCNK10 | |
| SCHEMBL3711733 | 0.65 | DHODH (0.57) | KMT2AMEN1POLBMAPTSMN1; SMN2 | |
| SCHEMBL23243427 | 0.65 | KDM4E (0.55) | KMT2AMEN1POLBMAPTCYP1A2 | |
| SCHEMBL31125276 | 0.65 | KDM4E (0.55) | KMT2AMEN1POLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947984-B | Preparation method of pranlukast | 烟台万润药业有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-108947984-B | Preparation method of pranlukast | 烟台万润药业有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-108947984-B | Preparation method of pranlukast | 烟台万润药业有限公司 | 2020-07-07 | — | — | CN | disclosed |