SCHEMBL1491944

SCHEMBL1491944

CCc1cc(Br)cc(CC)c1NC(=O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
KDM4E B2RXH2 3/20 0.54
TTR P02766 1/20 0.51
KMT2A Q03164 5/20 0.50
MEN1 O00255 3/20 0.50
KCNK3 O14649 2/20 0.50
KCNK9 Q9NPC2 2/20 0.50
TP53 P04637 1/20 0.50
LMNA P02545 1/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 3/20 0.47
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
HTT P42858 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12285477 0.84 KDM4E (0.54) ALDH1A1KDM4EKMT2AKCNK3KCNK9
Iodide SCHEMBL30758627 0.81 KDM4E (0.67) ALDH1A1KDM4EKMT2AMEN1KCNK3
SCHEMBL3661793 0.81 ALDH1A1 (0.44) ALDH1A1KDM4ELMNAHPGDMAPT
SCHEMBL13129140 0.77 KDM4E (0.50) ALDH1A1KDM4EKMT2AMEN1KCNK3
SCHEMBL19426861 0.75 KDM4E (0.55) ALDH1A1KDM4EKMT2AMEN1KCNK3
SCHEMBL15014133 0.75 HTT (0.54) ALDH1A1KDM4EKMT2AMEN1TP53
SCHEMBL27872677 0.74 ALDH1A1 (0.68) ALDH1A1KDM4EKMT2AMEN1KCNK3
SCHEMBL5946149 0.73 MEN1 (0.52) ALDH1A1KDM4ETTRKMT2AMEN1
SCHEMBL528445 0.73 KCNK3 (0.77) ALDH1A1KMT2AMEN1KCNK3KCNK9
SCHEMBL5493153 0.72 TTR (0.42) ALDH1A1KDM4ETTRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9735377-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 US disclosed
US-9735377-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 US disclosed
US-9735377-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 US disclosed
US-20170110676-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION 2017-04-20 US disclosed
US-20170110676-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION 2017-04-20 US disclosed
US-20170110676-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION 2017-04-20 US disclosed
US-20140042413-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2014-02-13 US disclosed
US-20140042413-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2014-02-13 US disclosed
US-20140042413-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2014-02-13 US disclosed
US-8586204-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2013-11-19 US disclosed
US-8586204-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2013-11-19 US disclosed
US-20110057559-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2011-03-10 US disclosed
US-20110057559-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2011-03-10 US disclosed
US-20110057559-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2011-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110057559-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY DDT, TPST2, NUDT1 ALDH1A1 901/4885KDM4E 2485/4885TTR 1488/4885
US-20170110676-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY NUDC, TEC, MAP1LC3C ALDH1A1 1636/4885KDM4E 3376/4885TTR 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.