Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 2/20 | 0.34 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597895 | 0.89 | SIRT2 (0.37) | SIRT5SIRT2SIRT1SIRT3NPC1 | |
| SCHEMBL21597894 | 0.89 | SIRT2 (0.37) | SIRT5SIRT2SIRT1SIRT3NPC1 | |
| SCHEMBL28687742 | 0.89 | SIRT5 (0.35) | SIRT5SIRT2SIRT1SMN1; SMN2ADAM10 | |
| SCHEMBL28687744 | 0.89 | SIRT5 (0.35) | SIRT5SIRT2SIRT1SMN1; SMN2ADAM10 | |
| SCHEMBL28444433 | 0.86 | FURIN (0.41) | SIRT5SIRT2SIRT1SIRT3NPC1 | |
| SCHEMBL28974940 | 0.85 | KLK7 (0.39) | SIRT5SIRT2SIRT1SIRT3SMN1; SMN2 | |
| SCHEMBL29211700 | 0.85 | SIRT1 (0.38) | SIRT5SIRT2SIRT1SIRT3SMN1; SMN2 | |
| SCHEMBL28974938 | 0.85 | KLK7 (0.39) | SIRT5SIRT2SIRT1SIRT3SMN1; SMN2 | |
| SCHEMBL28425028 | 0.85 | KLK7 (0.37) | SIRT5SIRT2SIRT1SIRT3SMN1; SMN2 | |
| SCHEMBL28425032 | 0.85 | KLK7 (0.37) | SIRT5SIRT2SIRT1SIRT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533778-B | Industrial production method of antibody-coupled drug connector | 上海皓元生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111533778-A | Industrial production method of antibody-conjugated drug linker | 上海皓元生物医药科技有限公司 | 2020-08-14 | — | — | CN | disclosed |