Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.38 |
| ▸ | FURIN | P09958 | 3/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29211699 | 1.00 | SIRT1 (0.38) | SIRT1SIRT2SIRT3FURINKLK7 | |
| SCHEMBL28974938 | 0.92 | KLK7 (0.39) | SIRT1SIRT2SIRT3FURINKLK7 | |
| SCHEMBL28425032 | 0.92 | KLK7 (0.37) | SIRT1SIRT2SIRT3FURINKLK7 | |
| SCHEMBL28974940 | 0.92 | KLK7 (0.39) | SIRT1SIRT2SIRT3FURINKLK7 | |
| SCHEMBL28425028 | 0.92 | KLK7 (0.37) | SIRT1SIRT2SIRT3FURINKLK7 | |
| SCHEMBL28681266 | 0.91 | FURIN (0.37) | SIRT1SIRT2SIRT3FURINKLK7 | |
| SCHEMBL29211789 | 0.91 | SIRT2 (0.48) | SIRT1SIRT2SIRT3FURINCASP3 | |
| SCHEMBL29211793 | 0.91 | SIRT2 (0.48) | SIRT1SIRT2SIRT3FURINCASP3 | |
| SCHEMBL28631982 | 0.87 | SIRT5 (0.44) | SIRT1SIRT2SIRT3SIRT5 | |
| SCHEMBL28444425 | 0.87 | SIRT5 (0.38) | SIRT1SIRT2SIRT3FURINKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801107-A | Benzazepine derivatives, conjugates containing same and application thereof | 上海迪诺医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |