Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106965 | 0.68 | ALDH1A1 (0.39) | ALDH1A1HPGDBCL2L1HSD17B10NAMPT | |
| SCHEMBL28347434 | 0.67 | ALDH1A1 (0.50) | ALDH1A1HPGDBCL2L1HSD17B10L3MBTL1 | |
| SCHEMBL8163489 | 0.66 | ALDH1A1 (0.40) | ALDH1A1HPGDBCL2L1HSD17B10NAMPT | |
| SCHEMBL7067472 | 0.65 | APAF1 (0.31) | — | |
| SCHEMBL11074497 | 0.63 | ALDH1A1 (0.41) | ALDH1A1HPGDBCL2L1HSD17B10L3MBTL1 | |
| SCHEMBL2990054 | 0.62 | — | — | |
| SCHEMBL30442890 | 0.61 | ALDH1A1 (0.67) | ALDH1A1HPGDBCL2L1HSD17B10L3MBTL1 | |
| SCHEMBL29623192 | 0.61 | ALDH1A1 (0.67) | ALDH1A1HPGDBCL2L1HSD17B10L3MBTL1 | |
| SCHEMBL28574 | 0.61 | ALDH1A1 (0.67) | ALDH1A1HPGDBCL2L1HSD17B10L3MBTL1 | |
| SCHEMBL5031420 | 0.60 | ALDH1A1 (0.35) | ALDH1A1HPGDBCL2L1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454248-A | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders | 阿尔维纳斯运营股份有限公司 | 2020-07-28 | — | — | CN | disclosed |