Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643337 | 0.73 | HTR3E (0.57) | ADRA1DADRA1AADRA1BLMNAMAPT | |
| SCHEMBL28445707 | 0.73 | MAPT (0.46) | ADRA1DADRA1AADRA1BLMNAMAPT | |
| SCHEMBL28449595 | 0.73 | ALDH1A1 (0.37) | ADRA1DADRA1AADRA1BLMNAMAPT | |
| SCHEMBL15261159 | 0.71 | MAPT (0.51) | LMNAMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL7899024 | 0.71 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BLMNAMAPT | |
| SCHEMBL8123113 | 0.70 | HRH4 (0.56) | ADRA1DADRA1AADRA1BLMNAMAPT | |
| SCHEMBL13279147 | 0.69 | HRH4 (0.61) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3391134 | 0.68 | SLC18A3 (0.60) | LMNAMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL21135498 | 0.68 | MAPT (0.60) | LMNAMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL230404 | 0.68 | HTR3E (0.53) | LMNAMAPTALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630048-A | Amidine and guanidine derivatives, preparation method and application thereof in medicines | 四川科伦博泰生物医药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |