Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238358 | 0.82 | ERN1 (0.41) | LMNA | |
| SCHEMBL25282164 | 0.79 | ERN1 (0.44) | — | |
| SCHEMBL5042198 | 0.79 | IDO1 (0.34) | — | |
| SCHEMBL3256391 | 0.77 | EPAS1 (0.36) | — | |
| SCHEMBL15969111 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL3548569 | 0.76 | ALDH1A1 (0.43) | LMNA | |
| SCHEMBL4521425 | 0.75 | MAOA (0.47) | LMNA | |
| SCHEMBL2253527 | 0.75 | CA12 (0.39) | — | |
| SCHEMBL7220710 | 0.75 | PRKDC (0.33) | LMNA | |
| SCHEMBL9828079 | 0.74 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601797-B | Benzopiperidine or heteroaryl piperidine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-111601797-A | Benzopiperidine or heteroaryl piperidine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2020-08-28 | — | — | CN | disclosed |