Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548569 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2MAPTCYP2A6 | |
| SCHEMBL28447338 | 0.74 | LMNA (0.30) | — | |
| SCHEMBL30887675 | 0.73 | RAB9A (0.56) | ALDH1A1HPGDSMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL5238358 | 0.73 | ERN1 (0.41) | ALDH1A1TP53HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL4521425 | 0.72 | MAOA (0.47) | ALDH1A1MAPTCYP2A6 | |
| SCHEMBL704145 | 0.71 | CA4 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5236553 | 0.70 | CA4 (0.40) | ALDH1A1TP53HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL25282164 | 0.70 | ERN1 (0.44) | ALDH1A1TP53CYP3A4MAPTHSD17B10 | |
| SCHEMBL7220710 | 0.69 | PRKDC (0.33) | ALDH1A1MAPTCA12CA1CA9 | |
| SCHEMBL8456921 | 0.69 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2MAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200736-B1 | PYRAZOLE ANALOGS OF MEVALONOLACTONE AND DERIVATIVES THEREOF, PROCESSES FOR THEIR PRODUCTION AND THEIR USE | SANDOZ AG (CH) | 1991-04-24 | — | — | EP | disclosed |
| US-4613610-A | TREATING ATHEROSCLEROSIS AND HYPERLIPEMIA | SANDOZ PHARMACEUTICALS CORP. (US) | 1986-09-23 | — | — | US | disclosed |