Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213441 | 0.83 | XIAP (0.47) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL3349545 | 0.83 | ACHE (0.47) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL5404613 | 0.82 | ACHE (0.46) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL6177893 | 0.78 | ACHE (0.63) | MAPTKDM4EALDH1A1ACHESLC22A12 | |
| SCHEMBL12193492 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNAACHEMYC | |
| SCHEMBL3350583 | 0.76 | ALDH1A1 (0.48) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL20178669 | 0.75 | ACHE (0.53) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL11977166 | 0.74 | SLC22A12 (0.70) | MAPTALDH1A1ACHESLC22A12MYC | |
| SCHEMBL12359557 | 0.74 | ACHE (0.41) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL4929256 | 0.73 | ALDH1A1 (0.57) | MEN1KMT2AMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074816-B | Heterocyclic derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2020-07-17 | — | — | CN | disclosed |