Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21882598 | 0.88 | XIAP (0.48) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL3350901 | 0.86 | XIAP (0.47) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL13214309 | 0.85 | XIAP (0.50) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL15418016 | 0.85 | XIAP (0.46) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL27951583 | 0.84 | REN (0.48) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL28447449 | 0.83 | MEN1 (0.46) | MEN1KMT2AKDM4EALDH1A1ALOX15 | |
| SCHEMBL28532040 | 0.82 | MEN1 (0.49) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL2502232 | 0.80 | KDM4E (0.59) | XIAPBIRC2MEN1KMT2AKDM4E | |
| SCHEMBL23754421 | 0.80 | ACHE (0.57) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL30027318 | 0.80 | ACHE (0.57) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589963-B2 | Drug salt thereof show a hypoglycemic action, a blood hypolipidemic action, an insulin resistance-improving action and a PPAR activating action, and are useful as a hypoglycemic agent, a hypolipidemic agent, an insulin | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| US-20030027836-A1 | Novel heterocyclic compounds and salts thereof and medicinal use of the same | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1236719-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND SALTS THEREOF AND MEDICINAL USE OF THE SAME | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2002-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027836-A1 | Novel heterocyclic compounds and salts thereof and medicinal use of the same | GPR119, PPARA, PPARG | XIAP 4426/4885BIRC2 4621/4885MEN1 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.