Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023929 | 0.81 | ALDH1A1 (0.59) | MAPTALDH1A1MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL28446570 | 0.79 | MAPK1 (0.64) | MAPTALDH1A1MAPK1MAOBSMN1; SMN2 | |
| SCHEMBL29946473 | 0.77 | MAPT (0.46) | MAPTALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL11291316 | 0.74 | PIN1 (0.51) | MAPTALDH1A1HTTMAOBSMN1; SMN2 | |
| SCHEMBL6660068 | 0.74 | THRA (0.54) | MAPTALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL3227962 | 0.74 | MAPK1 (0.55) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL28439509 | 0.74 | ALDH1A1 (0.49) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL22069567 | 0.74 | HSPB1 (0.56) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL22041609 | 0.74 | ALDH1A1 (0.49) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL6273882 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1MAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452167-B | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-08-21 | — | — | CN | disclosed |