Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 3/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345395 | 1.00 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL30345445 | 0.87 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6EGLN1 | |
| SCHEMBL28446135 | 0.87 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6EGLN1 | |
| SCHEMBL11089737 | 0.85 | VNN1 (0.55) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL28897243 | 0.84 | EGLN1 (0.50) | EGLN1 | |
| SCHEMBL30345304 | 0.84 | EGLN1 (0.50) | EGLN1 | |
| SCHEMBL28452694 | 0.83 | EGLN1 (0.47) | EGLN1EGLN3LMNA | |
| SCHEMBL30345442 | 0.83 | EGLN1 (0.47) | EGLN1EGLN3LMNA | |
| SCHEMBL28442587 | 0.81 | EGLN1 (0.64) | EGLN1EGLN3 | |
| SCHEMBL30345459 | 0.81 | EGLN1 (0.64) | EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | claimed |
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | disclosed |