Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455463 | 0.81 | FBP1 (0.45) | PKMLMNAHSD17B10NPSR1MAPT | |
| SCHEMBL28451878 | 0.77 | NPSR1 (0.52) | PKMNPSR1RAB9AKMT2AMAPK1 | |
| SCHEMBL3909244 | 0.76 | NPC1 (0.50) | PKMLMNAHSD17B10RAB9AMAPK1 | |
| SCHEMBL9530474 | 0.76 | MAPK1 (0.53) | PKMHSD17B10NPSR1MAPTRAB9A | |
| SCHEMBL30688819 | 0.75 | XBP1 (0.57) | LMNAXBP1NPSR1MAPTAGTR1 | |
| SCHEMBL8863159 | 0.75 | XBP1 (0.57) | LMNAXBP1NPSR1MAPTAGTR1 | |
| SCHEMBL3900305 | 0.71 | ALDH1A1 (0.69) | PKMLMNAHSD17B10NPSR1MAPT | |
| SCHEMBL5019834 | 0.71 | TSHR (0.55) | LMNAXBP1NPSR1MAPTAGTR1 | |
| SCHEMBL29241799 | 0.71 | KDM4E (0.64) | PKMLMNAHSD17B10MAPTRAB9A | |
| SCHEMBL27589778 | 0.70 | SLC6A2 (0.54) | LMNAXBP1NPSR1MAPTAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602548-B | Myricetin derivative containing amide thioether thiadiazole, preparation method and application | 贵州大学 | 2020-09-01 | — | — | CN | disclosed |