Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL105952 | 0.97 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL21489542 | 0.92 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL30776749 | 0.92 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28452810 | 0.92 | LMNA (0.56) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL105192 | 0.92 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL107714 | 0.92 | SLC22A6 (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL105756 | 0.92 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL23780654 | 0.89 | LMNA (0.61) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL2380307 | 0.89 | TSHR (0.67) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL6135890 | 0.89 | TSHR (0.67) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111569680-B | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2021-03-19 | — | — | CN | claimed |
| CN-111569680-B | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-111569680-A | Polyarylether ultrafiltration membrane, nanofiltration membrane, preparation method and method for reversible conversion of ultrafiltration membrane and nanofiltration membrane | 四川大学 | 2020-08-25 | — | — | CN | disclosed |