Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 6/20 | 0.52 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.52 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.52 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.52 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL4094376 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL9642090 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Pimelic Acid SCHEMBL30384892 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL21489542 | 0.97 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL105756 | 0.97 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| Potassium Ion SCHEMBL30384886 | 0.94 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL31148332 | 0.94 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL29049531 | 0.94 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL29070842 | 0.94 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL2380307 | 0.94 | TSHR (0.67) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-219721965-U | Sebacic acid acidification crystallization precipitation equipment | 山西振钢生物科技股份有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-113264823-B | Method for improving stability of sebacic acid | 丰益高分子材料（连云港）有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-113354532-B | Method for preparing high-purity sebacic acid | 丰益高分子材料（连云港）有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-107446663-B | Rolling bearing | 美蓓亚三美株式会社 | 2022-01-07 | — | — | CN | claimed |
| CN-113354532-A | Method for preparing high-purity sebacic acid | 丰益高分子材料（连云港）有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-113264823-A | Method for improving stability of sebacic acid | 丰益高分子材料（连云港）有限公司 | 2021-08-17 | — | — | CN | claimed |
| US-9217471-B2 | Lubricant composition and bearing using same | NTN CORPORATION (JP) | 2015-12-22 | — | — | US | claimed |
| US-20120277132-A1 | LUBRICANT COMPOSITION AND BEARING USING SAME | NTN CORPORATION (JP) | 2012-11-01 | — | — | US | claimed |
| CN-224236124-U | Precipitation device of sebacic acid | 衡水京华化工有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122032443-A | Device for preparing sebacic acid by pyrolysis of ricinoleic acid | 山西振钢生物科技股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-222889743-U | Homogenization preheating device before disodium salt feed liquid acidizing in sebacic acid production | 山西振钢生物科技股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-12281066-B1 | Device and process for preparing sebacic acid through electromagnetic induction heating coupled with dry constant-temperature alkaline hydrolysis | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2025-04-22 | — | — | US | disclosed |
| CN-222401435-U | Cracking kettle for preparing sebacic acid by cracking castor oil | 山西振钢生物科技股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-221815371-U | Counter-flow type double-tank device for recycling fatty acid | 山西振钢生物科技股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-102351682-A | Preparation method for sebacic acid | SHANGHAICHEM ENGINEERING INC | 2012-02-15 | — | — | CN | disclosed |
| CN-101988004-A | Lubricating grease antirust anticorrosive additive | TIANJIN GONGBO TECHNOLOGY DEV CO LTD | 2011-03-23 | — | — | CN | disclosed |
| CN-1303053-C | Method for realizing cleansing production of sebacic acid by using clearing resin | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2007-03-07 | — | — | CN | disclosed |
| CN-1633440-A | Branched-chain lipophilic molecule derivatives and uses thereof | DPHARM LTD (IL) | 2005-06-29 | — | — | CN | disclosed |
| US-20050009713-A1 | Lubricant composition and bearing using same | NTN CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1496103-A2 | Lubricant composition and bearing using same | NTN CORPORATION (JP) | 2005-01-12 | — | — | EP | disclosed |