Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449247 | 0.96 | PDE4A (0.40) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28453210 | 0.80 | TSHR (0.43) | HTR2CSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL28451755 | 0.76 | MAPT (0.46) | HTR2CSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL28444292 | 0.75 | KMT2A (0.44) | NPSR1ALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL28453362 | 0.75 | KMT2A (0.46) | HTR2CSMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL28443106 | 0.74 | MEN1 (0.37) | SMN1; SMN2ALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL6236056 | 0.74 | CHRM4 (0.49) | HTR2CSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL28452276 | 0.73 | MEN1 (0.39) | HTR2CSMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL28898040 | 0.73 | MEN1 (0.39) | HTR2CSMN1; SMN2ALDH1A1MAPTALOX15 | |
| SCHEMBL28457314 | 0.73 | GAA (0.41) | HTR2CSMN1; SMN2NPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156789-B | Synthetic method of azacyclo-quinazoline compound | 东华理工大学 | 2020-09-04 | — | — | CN | disclosed |