Benzene

Benzene

SCHEMBL28453035

CCCCCCCCc1cccc2c1-c1ccccc1C2.NC=O.c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
SAE1 Q9UBE0 2/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
CYSLTR2 Q9NS75 7/20 0.41
CYSLTR1 Q9Y271 7/20 0.41
DRD2 P14416 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28975089 0.92 LIPG (0.46) NR1H2NR1H3BIDMCL1BCL2L1
SCHEMBL29508750 0.92 LIPG (0.46) NR1H2NR1H3BIDMCL1BCL2L1
SCHEMBL2416249 0.90 LIPG (0.44) NR1H2NR1H3BIDMCL1BCL2L1
SCHEMBL9162757 0.86 DRD2 (0.44) NR1H2NR1H3DRD2SLC6A2HTR2A
SCHEMBL5256511 0.79 DRD2 (0.38) DRD2
Formamide SCHEMBL28187451 0.78 LIPG (0.56) NR1H2NR1H3BIDMCL1BCL2L1
SCHEMBL7189694 0.78 DRD3 (0.51) DRD2SLC6A2SLC6A4KDM4EMAPT
SCHEMBL7018897 0.77 DRD2 (0.38) DRD2
SCHEMBL21694426 0.76 DRD2 (0.48) DRD2KDM4EMAPTALOX15HSD17B10
SCHEMBL407782 0.75 PNMT (0.57) NR1H2NR1H3BIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485582-B Fluorenone-based organogel molecule and preparation method and application thereof 南京工业大学 2020-07-17 CN disclosed