SCHEMBL2416249

SCHEMBL2416249

CCCCCc1cccc2c1-c1ccccc1C2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.44
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
DRD2 P14416 2/20 0.43
DRD4 P21917 1/20 0.43
DRD3 P35462 1/20 0.43
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
SLC6A4 P31645 1/20 0.41
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
PNMT P11086 1/20 0.39
ELANE P08246 2/20 0.39
CTSG P08311 2/20 0.39
CYSLTR2 Q9NS75 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508750 0.98 LIPG (0.46) LIPGNR1H2NR1H3DRD2DRD4
SCHEMBL28975089 0.98 LIPG (0.46) LIPGNR1H2NR1H3DRD2DRD4
SCHEMBL9162757 0.95 DRD2 (0.44) LIPGNR1H2NR1H3DRD2DRD4
Benzene SCHEMBL28453035 0.90 NR1H2 (0.43) LIPGNR1H2NR1H3DRD2SLC6A2
SCHEMBL7189694 0.86 DRD3 (0.51) DRD2DRD4DRD3SLC6A2SLC6A4
SCHEMBL21694426 0.81 DRD2 (0.48) DRD2DRD4DRD3ALOX5ALDH1A1
SCHEMBL5823386 0.81 PNMT (0.58) LIPGNR1H2NR1H3DRD2DRD4
SCHEMBL8662797 0.80 DRD2 (0.43) DRD2DRD4DRD3ALDH1A1CYP1A2
SCHEMBL6571147 0.80 NR1H2 (0.35) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL407782 0.79 PNMT (0.57) LIPGNR1H2NR1H3DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8021767-B2 4-arylfluorene compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-09-20 US claimed
US-20090134788-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-28 US claimed
CN-101432251-A 4-arylfluorene compound and organic light emitting device using the same CANON KK (JP) 2009-05-13 CN claimed
EP-2013158-A4 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KK (JP) 2009-04-22 EP claimed
EP-2013158-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME Canon Kabushiki Kaisha (JP) 2009-01-14 EP claimed
WO-2007125809-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2007-11-08 WO claimed
US-8021767-B2 4-arylfluorene compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-09-20 US disclosed
US-8021767-B2 4-arylfluorene compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-09-20 US disclosed
US-8021767-B2 4-arylfluorene compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-09-20 US disclosed
US-20090134788-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-28 US disclosed
US-20090134788-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2009-05-28 US disclosed
CN-101432251-A 4-arylfluorene compound and organic light emitting device using the same CANON KK (JP) 2009-05-13 CN disclosed
CN-101432251-A 4-arylfluorene compound and organic light emitting device using the same CANON KK (JP) 2009-05-13 CN disclosed
EP-2013158-A4 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KK (JP) 2009-04-22 EP disclosed
EP-2013158-A4 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KK (JP) 2009-04-22 EP disclosed
EP-2013158-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME Canon Kabushiki Kaisha (JP) 2009-01-14 EP disclosed
EP-2013158-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME Canon Kabushiki Kaisha (JP) 2009-01-14 EP disclosed
JP-2007314506-A 4-ARYL FLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CANON INC 2007-12-06 JP disclosed
WO-2007125809-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2007-11-08 WO disclosed
WO-2007125809-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2007-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090134788-A1 4-ARYLFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME AFF4, PPOX, AFF2 LIPG 2780/4885NR1H2 1326/4885NR1H3 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.