Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452078 | 0.79 | MAPK1 (0.56) | NPSR1MAPK1PKMPAX8ATM | |
| SCHEMBL28461401 | 0.79 | MAPK1 (0.51) | NPSR1MAPK1PKMPAX8ATM | |
| SCHEMBL9530474 | 0.74 | MAPK1 (0.53) | NPSR1MAPK1PKMPAX8ATM | |
| SCHEMBL8101641 | 0.72 | PKM (0.47) | NPSR1MAPK1PKMPAX8ATM | |
| SCHEMBL28814199 | 0.72 | GAA (0.68) | NPSR1MAPK1PKMHSD17B10HPGD | |
| SCHEMBL28434316 | 0.71 | MYC (0.42) | HSD17B10ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL1821527 | 0.70 | NPSR1 (0.63) | NPSR1MAPK1PKMPAX8ATM | |
| SCHEMBL28451878 | 0.70 | NPSR1 (0.52) | NPSR1MAPK1PKMPAX8ATM | |
| SCHEMBL576094 | 0.70 | ACHE (0.53) | ALDH1A1TDP1L3MBTL1HAO1 | |
| SCHEMBL31038144 | 0.68 | ALDH1A1 (0.58) | NPSR1MAPK1ATMFBP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602548-B | Myricetin derivative containing amide thioether thiadiazole, preparation method and application | 贵州大学 | 2020-09-01 | — | — | CN | disclosed |