Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28458984 | 0.98 | LTA4H (0.42) | LTA4HHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8473466 | 0.77 | ALOX12 (0.41) | LTA4HALDH1A1TSHRCTSVCTSL | |
| SCHEMBL13244744 | 0.76 | HTR1A (0.46) | HTR1ASLC6A2SLC6A3SLC6A4SIGMAR1 | |
| SCHEMBL1828600 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL28944030 | 0.72 | GAA (0.41) | LTA4HHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL18553759 | 0.71 | LTA4H (0.58) | LTA4HHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15517942 | 0.71 | LTA4H (0.44) | LTA4HHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8611203 | 0.70 | LTA4H (0.52) | LTA4HHTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL532873 | 0.69 | NPC1 (0.50) | HTR1ASLC6A2SLC6A3SLC6A4SIGMAR1 | |
| SCHEMBL3029842 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137508-B | 5-HT2CReceptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-107428764-B | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2020-09-11 | — | — | CN | disclosed |