Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631712 | 0.90 | GAA (0.50) | LMNATHRBGAAKDM4ESMN1; SMN2 | |
| SCHEMBL7434290 | 0.82 | KCNQ3 (0.53) | LMNAGAAKDM4ESMN1; SMN2POLB | |
| SCHEMBL10774088 | 0.82 | CTSS (0.51) | LMNAGAAKDM4ESTAT1RAB9A | |
| SCHEMBL7434407 | 0.82 | GAA (0.60) | LMNAGLAGAAKDM4ERAB9A | |
| SCHEMBL28799774 | 0.79 | LMNA (0.46) | LMNAGLAGAAKDM4ESTAT1 | |
| SCHEMBL22347298 | 0.79 | MEN1 (0.51) | LMNAGAARAB9APOLBMAOB | |
| SCHEMBL27087783 | 0.77 | HDAC3 (0.56) | LMNAGLAMEN1KMT2A | |
| SCHEMBL25780269 | 0.77 | EPHX2 (0.49) | SLC26A6GAAKDM4ERAB9ATDP1 | |
| SCHEMBL29176912 | 0.76 | MAOB (0.55) | SLC26A6LMNAGLAMAOBMEN1 | |
| SCHEMBL5939725 | 0.75 | SCN8A (0.52) | SLC26A6EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531721-B | Fused tricyclic pyrazole derivatives for modulating farnesoid X receptors | 诺华股份有限公司 | 2020-07-17 | — | — | CN | disclosed |