Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.51 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434407 | 0.83 | GAA (0.60) | CYP1A2MAPK1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28453979 | 0.82 | SLC26A6 (0.46) | GAAKDM4ETDP1EPHX2POLB | |
| SCHEMBL1668799 | 0.79 | GAA (0.50) | KCNQ4KCNQ5GAAKDM4EKMT2A | |
| SCHEMBL1240060 | 0.79 | ALDH1A1 (0.51) | CYP1A2CYP2C19KDM4ETP53POLB | |
| SCHEMBL8631712 | 0.79 | GAA (0.50) | CYP1A2MAPK1ESR1CYP3A4CYP2C9 | |
| SCHEMBL8338756 | 0.78 | LMNA (0.49) | KDM4ETP53POLBKMT2AHPGD | |
| SCHEMBL679354 | 0.77 | GAA (0.71) | KCNQ3KCNQ2CYP1A2KCNQ4KCNQ5 | |
| SCHEMBL15996898 | 0.76 | KCNQ3 (0.70) | KCNQ3KCNQ2CYP1A2MAPK1KCNQ4 | |
| SCHEMBL28799782 | 0.75 | CYP1A2 (0.47) | KCNQ3KCNQ2CYP1A2MAPK1KCNQ4 | |
| SCHEMBL3176370 | 0.74 | LMNA (0.51) | KCNQ3KCNQ2CYP1A2MAPK1KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |