Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | NPY4R | P50391 | 4/20 | 0.32 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22618780 | 1.00 | NMT2 (0.37) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL27189813 | 0.92 | HDAC3 (0.35) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL23193234 | 0.91 | FURIN (0.32) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL22618807 | 0.91 | FURIN (0.32) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL22618769 | 0.91 | HDAC3 (0.34) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL26755869 | 0.87 | NMT2 (0.34) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL26758333 | 0.87 | NMT2 (0.34) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL24872282 | 0.82 | FURIN (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23355149 | 0.80 | CTSL (0.42) | FURINHTTNPY5RNPY4RNPY1R | |
| SCHEMBL15692124 | 0.80 | NMT2 (0.45) | NMT2NMT1FURINNPY5RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698414-A | Bioactive substance conjugate and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113683622-A | Bioactive substance conjugate and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-113651831-A | Bioactive substance conjugate and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113603703-A | Bioactive substance conjugate and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-111295389-B | Bioactive substance conjugate and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-111295389-A | Bioactive substance conjugate and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-06-16 | — | — | CN | disclosed |