Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455283 | 0.86 | ADRA1D (0.56) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL8828501 | 0.83 | ADRA1D (0.50) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL1902821 | 0.81 | HPGD (0.69) | KDM4EGLAPOLBALDH1A1HPGD | |
| SCHEMBL14470975 | 0.81 | KDM4E (0.51) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL20274413 | 0.79 | KDM4E (0.50) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL5392212 | 0.79 | KDM4E (0.58) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL5258999 | 0.79 | MAPT (0.60) | ADRA1AADRA1DADRA1BALDH1A1HPGD | |
| SCHEMBL29212431 | 0.79 | ADRA1D (0.52) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL2493412 | 0.78 | IDO1 (0.50) | ADRA1AADRA1DADRA1BKDM4EGLA | |
| SCHEMBL963365 | 0.78 | L3MBTL1 (0.49) | ADRA1AADRA1DADRA1BKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |