Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544472 | 0.91 | KDM4E (0.59) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL1067857 | 0.91 | KDM4E (0.59) | KDM4EALDH1A1HPGDGLAGAA | |
| Methane SCHEMBL27535529 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL3694892 | 0.79 | KMT2A (0.47) | KDM4EALDH1A1HPGDGLAGAA | |
| Acridine SCHEMBL11600717 | 0.78 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDGLAGAA | |
| Acridine SCHEMBL10831095 | 0.78 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL3702685 | 0.77 | KMT2A (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL3709925 | 0.77 | KMT2A (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL3694868 | 0.77 | KMT2A (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL366220 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119770669-A | Preparation method and application of targeted co-delivery system based on pMMP-1 and hydroxychloroquinoline | 中国人民解放军空军军医大学 | 2025-04-08 | — | — | CN | claimed |
| CN-117122576-A | Preparation method and application of hydroxychloroquinoline targeted nano drug delivery system | 中国人民解放军空军军医大学 | 2023-11-28 | — | — | CN | claimed |
| CN-119770669-A | Preparation method and application of targeted co-delivery system based on pMMP-1 and hydroxychloroquinoline | 中国人民解放军空军军医大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-117122576-A | Preparation method and application of hydroxychloroquinoline targeted nano drug delivery system | 中国人民解放军空军军医大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-112745263-B | Preparation method of hydroxychloroquine | 南京济群医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-111635358-B | Preparation method of hydroxychloroquine | 北京成宇化工有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113185459-A | Hydroxychloroquine sulfate and preparation method thereof | 江西国药有限责任公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112745263-A | Preparation method of hydroxychloroquine | 南京济群医药科技股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-111635358-A | Preparation method of hydroxychloroquine | 北京成宇化工有限公司 | 2020-09-08 | — | — | CN | disclosed |