Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184417 | 0.86 | GPR119 (0.40) | — | |
| SCHEMBL28452438 | 0.86 | GPR119 (0.40) | — | |
| SCHEMBL16914281 | 0.75 | NAMPT (0.31) | NAMPT | |
| SCHEMBL28446272 | 0.74 | GPR119 (0.39) | NAMPT | |
| SCHEMBL31184121 | 0.74 | GPR119 (0.39) | NAMPT | |
| SCHEMBL28456569 | 0.74 | — | — | |
| SCHEMBL28444655 | 0.73 | — | — | |
| SCHEMBL2980571 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL28356333 | 0.69 | GPR119 (0.38) | NAMPT | |
| SCHEMBL31184402 | 0.69 | GPR119 (0.38) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625028-A | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-107787323-B | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2020-09-01 | — | — | CN | disclosed |