Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676833 | 0.85 | ALDH1A1 (0.47) | NOTUMNPSR1ALDH1A1HPGDHTT | |
| SCHEMBL3066977 | 0.82 | NOTUM (0.49) | NOTUMNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL28464362 | 0.81 | CA12 (0.48) | ALDH1A1HTTTDP1LMNAKMT2A | |
| SCHEMBL28467697 | 0.80 | MEN1 (0.46) | NPC1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL31261822 | 0.76 | TDP1 (0.41) | NOTUMNPSR1ALDH1A1HPGDHTT | |
| SCHEMBL28454695 | 0.74 | KDM4E (0.50) | NPC1RAB9AALDH1A1HPGDHTT | |
| SCHEMBL6363008 | 0.71 | TDP1 (0.46) | NOTUMNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL30910832 | 0.71 | TSHR (0.52) | NOTUMNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL172737 | 0.70 | PTGS2 (0.59) | ALDH1A1HPGDHTTTDP1LMNA | |
| SCHEMBL30179347 | 0.70 | PTGS2 (0.59) | ALDH1A1HPGDHTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |
| CN-111587239-A | Method for producing lactam compound and lactam compound produced by same | 基础科学研究院 | 2020-08-25 | — | — | CN | disclosed |