Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408533 | 0.85 | KMT2A (0.45) | MEN1KMT2APKMSMN1; SMN2LMNA | |
| SCHEMBL28457993 | 0.80 | NOTUM (0.41) | MEN1KMT2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL28464362 | 0.80 | CA12 (0.48) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7844169 | 0.78 | LMNA (0.40) | MEN1KMT2APKMSMN1; SMN2LMNA | |
| SCHEMBL11488531 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2APKMSMN1; SMN2LMNA | |
| SCHEMBL16220948 | 0.72 | RAB9A (0.53) | MEN1KMT2ASMN1; SMN2LMNAHDAC6 | |
| SCHEMBL28454695 | 0.72 | KDM4E (0.50) | KMT2ASMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL5790498 | 0.72 | MAPT (0.46) | MEN1KMT2APKMSMN1; SMN2LMNA | |
| SCHEMBL29816549 | 0.71 | PTGS2 (0.57) | MEN1KMT2APKMSMN1; SMN2LMNA | |
| SCHEMBL198168 | 0.71 | PTGS2 (0.57) | MEN1KMT2APKMSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-A | Method for producing lactam compound and lactam compound produced by same | 基础科学研究院 | 2020-08-25 | — | — | CN | disclosed |