Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115344 | 0.85 | MTNR1A (0.53) | CA12CA1CA2CA4CA7 | |
| SCHEMBL28454695 | 0.84 | KDM4E (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28457993 | 0.81 | NOTUM (0.41) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL28467697 | 0.80 | MEN1 (0.46) | ALDH1A1POLBSMN1; SMN2MAPTKMT2A | |
| 1,2-Dimethoxybenzene SCHEMBL28254681 | 0.78 | CA1 (0.65) | CA12CA1CA2CA4CA7 | |
| 1,2-Dimethoxybenzene SCHEMBL28118612 | 0.77 | CA1 (0.72) | CA12CA1CA2CA4CA7 | |
| 1,2-Dimethoxybenzene SCHEMBL27898360 | 0.77 | CA1 (0.72) | CA12CA1CA2CA4CA7 | |
| SCHEMBL27991551 | 0.76 | MAPT (0.51) | CA12CA1CA2CA4CA7 | |
| 1,2-Dimethoxybenzene SCHEMBL27470563 | 0.75 | CA1 (0.68) | CA12CA1CA2CA4CA7 | |
| SCHEMBL26805580 | 0.75 | METAP2 (0.42) | MTNR1AMTNR1BALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |
| CN-111587239-A | Method for producing lactam compound and lactam compound produced by same | 基础科学研究院 | 2020-08-25 | — | — | CN | disclosed |