Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849408 | 0.83 | GPR84 (0.50) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2853505 | 0.79 | RXFP1 (0.61) | SOS1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2845799 | 0.78 | MEN1 (0.63) | ALOX5SOS1MEN1KMT2AALDH1A1 | |
| SCHEMBL15366577 | 0.76 | ALOX5 (0.62) | ALOX5SOS1MEN1KMT2AALDH1A1 | |
| SCHEMBL5682598 | 0.75 | KMT2A (0.44) | ALOX5SOS1MEN1KMT2AALDH1A1 | |
| SCHEMBL2847759 | 0.71 | MEN1 (0.58) | SOS1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27916683 | 0.70 | ALOX5 (0.60) | ALOX5SOS1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL379864 | 0.70 | KDM4E (0.48) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| Naphthalene SCHEMBL1132213 | 0.70 | HSD17B10 (0.55) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2848560 | 0.70 | ALDH1A1 (0.62) | ALOX5SOS1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240425-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009100925-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |