SCHEMBL28458248

SCHEMBL28458248

OB(O)c1ccc(C2(c3ccccc3)N=c3ccccc3=N2)cc1F

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28458385 0.84 BACE1 (0.33) BACE1
SCHEMBL28468752 0.77 BACE1 (0.36) BACE1
SCHEMBL11264366 0.73 LMNA (0.38) BACE1
SCHEMBL28481185 0.72 ENPP2 (0.36) BACE1
SCHEMBL28473610 0.72 CA2 (0.38) BACE1
SCHEMBL216066 0.71 LMNA (0.35) BACE1
SCHEMBL20450161 0.71 KDM4E (0.34) BACE1
SCHEMBL28462056 0.70 CA2 (0.42) BACE1
SCHEMBL39406 0.65 CES2 (0.43)
SCHEMBL29395656 0.65 CES2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108129394-B Organic electroluminescent material and preparation method and application thereof 北京燕化集联光电技术有限公司 2020-09-15 CN disclosed