SCHEMBL28458290

SCHEMBL28458290

C=CC(=O)OC(C)c1ccccc1OP(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
PDE3A Q14432 1/20 0.42
HSD17B10 Q99714 1/20 0.42
INPPL1 O15357 4/20 0.39
INPP5A Q14642 4/20 0.39
INPP5B P32019 2/20 0.39
HCAR2 Q8TDS4 1/20 0.36
AKT1 P31749 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
CYP1A2 P05177 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTR2A P28223 1/20 0.33
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819112 0.84 HCAR2 (0.41) HCAR2THRATHRBCYP1A2TSHR
SCHEMBL7189816 0.84 POLB (0.45) KDM4EHCAR2THRATHRBPOLB
SCHEMBL28470454 0.81 TSHR (0.44) KDM4EALDH1A1HPGDHSD17B10HCAR2
SCHEMBL5939259 0.81 HPGD (0.42) SRCKDM4EUSP2ALDH1A1HPGD
SCHEMBL28241612 0.80 L3MBTL1 (0.44) KDM4EUSP2ALDH1A1THRATHRB
SCHEMBL7138666 0.79 HCAR2 (0.37) HCAR2THRATHRBCYP1A2TSHR
SCHEMBL22471703 0.77 SRC (0.41) SRCKDM4EUSP2ALDH1A1HPGD
SCHEMBL3684997 0.76 HCAR2 (0.41) KDM4EALDH1A1HCAR2AKT1THRA
SCHEMBL1906054 0.76 GABRA1 (0.46) HCAR2AKT1THRATHRBCYP1A2
SCHEMBL224271 0.75 INPPL1 (0.52) SRCKDM4EUSP2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929180-A Dental resin-modified glass ionomer compositions and kits comprising the same 登士柏西诺德公司 2022-08-19 CN claimed
EP-4717248-A2 MANUFACTURING METHOD OF RESIN BLANK FOR DENTAL CUTTING AND MACHINING Shofu Inc. (JP) 2026-04-01 EP disclosed
EP-3682862-B1 CURABLE DENTAL COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-11-20 EP disclosed
US-20240299258-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-09-12 US disclosed
CN-118510478-A Curable composition for dental use, and dental patch comprising base material and resin layer 可乐丽则武齿科株式会社 2024-08-16 CN disclosed
EP-4364718-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-05-08 EP disclosed
CN-117597099-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-02-23 CN disclosed
US-20240034890-A1 ACRYLIC RESIN-MODIFIED SILICA PARTICLES, COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2024-02-01 US disclosed
EP-4306485-A1 ACRYLIC RESIN-MODIFIED SILICA PARTICLES, COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM Kansai Paint Co., Ltd (JP) 2024-01-17 EP disclosed
WO-2023167201-A1 ACTIVE ENERGY RAY-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT 株式会社カネカ 2023-09-07 WO disclosed
CN-115068346-A Dental photocurable composition having excellent handling properties and storage stability 株式会社松风 2022-09-20 CN disclosed
CN-115068348-A Curable composition for dental use having excellent storage stability 株式会社松风 2022-09-20 CN disclosed
WO-2022190464-A1 ACRYLIC RESIN-MODIFIED SILICA PARTICLES, COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM 関西ペイント株式会社 2022-09-15 WO disclosed
CN-114746523-A Coating composition and method for forming multilayer coating film 关西涂料株式会社 2022-07-12 CN disclosed
WO-2022124029-A1 POWDER MIXTURE FOR SPRAYING INTO TOOTH SURFACE OR INTO GINGIVAL SULCUS/PERIODONTAL POCKET 株式会社松風 2022-06-16 WO disclosed
CN-110546172-B Ultraviolet absorbing coating material and film coated with the same 新中村化学工业株式会社 2022-04-15 CN disclosed
CN-106963656-B Block composite material for dental cutting having fiber-containing material with multilayer structure having different transparency 株式会社松风 2022-02-22 CN disclosed
CN-109890344-B Subpackaged dental adhesive 可乐丽则武齿科株式会社 2022-02-22 CN disclosed
CN-111743783-A Double-paste type dental resin reinforced glass ion cement composition 株式会社松风 2020-10-09 CN disclosed
CN-111743782-A Powder-liquid type dental resin reinforced glass ionomer cement composition 株式会社松风 2020-10-09 CN disclosed