Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189816 | 0.85 | POLB (0.45) | HCAR2THRBTHRAPOLBHTT | |
| SCHEMBL9819112 | 0.85 | HCAR2 (0.41) | HCAR2THRBTHRATSHRCYP1A2 | |
| SCHEMBL28470454 | 0.82 | TSHR (0.44) | HCAR2THRBTHRATSHRCYP1A2 | |
| SCHEMBL28241612 | 0.81 | L3MBTL1 (0.44) | THRBTHRANPSR1L3MBTL1 | |
| SCHEMBL28458290 | 0.79 | SRC (0.42) | HCAR2THRBTHRATSHRCYP1A2 | |
| SCHEMBL1906054 | 0.77 | GABRA1 (0.46) | HCAR2THRBTHRATSHRCYP1A2 | |
| SCHEMBL3684997 | 0.77 | HCAR2 (0.41) | HCAR2THRBTHRATSHRCYP1A2 | |
| SCHEMBL8038710 | 0.76 | HCAR2 (0.41) | HCAR2THRBTHRATSHRCYP1A2 | |
| SCHEMBL8549851 | 0.75 | HCAR2 (0.43) | HCAR2THRBTSHRHTT | |
| SCHEMBL3173706 | 0.74 | LMNA (0.40) | HCAR2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377026-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2025-08-05 | — | — | US | claimed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | claimed |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | KURARAY NORITAKE DENTAL INC. (JP) | 2026-05-12 | — | — | US | disclosed |
| EP-4725470-A1 | CURABLE DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-12527725-B2 | Solvent-free dental adhesive composition | KURARAY NORITAKE DENTAL INC. (JP) | 2026-01-20 | — | — | US | disclosed |
| EP-4649938-A1 | DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2025-11-19 | — | — | EP | disclosed |
| US-12377026-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2025-08-05 | — | — | US | disclosed |
| US-20250213433-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | KURARAY NORITAKE DENTAL INC. (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250186309-A1 | DENTAL CURABLE COMPOSITION AND DENTAL KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2025-06-12 | — | — | US | disclosed |
| US-20250064687-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | KURARAY NORITAKE DENTAL INC. (JP) | 2025-02-27 | — | — | US | disclosed |
| EP-4505993-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | Kuraray Noritake Dental Inc. (JP) | 2025-02-12 | — | — | EP | disclosed |
| EP-3566689-B1 | DENTAL ADHESIVE COMPOSITION INCLUDING CHAIN TRANSFER AGENT | SHOFU INC (JP) | 2021-03-17 | — | — | EP | disclosed |
| US-20210007938-A1 | LOW WATER-SENSITIVE DENTAL COMPOSITION | SHOFU INC. (JP) | 2021-01-14 | — | — | US | disclosed |
| EP-3733151-A1 | LOW-WATER-SENSITIVE DENTAL COMPOSITION | Shofu Inc. (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3566689-A2 | DENTAL ADHESIVE COMPOSITION INCLUDING CHAIN TRANSFER AGENT | Shofu Inc. (JP) | 2019-11-13 | — | — | EP | disclosed |
| US-10149802-B2 | Filler characterized by acidic polymer treatment method | SHOFU INC. (JP) | 2018-12-11 | — | — | US | disclosed |
| US-20160213576-A1 | FILLER CHARACTERIZED BY ACIDIC POLYMER TREATMENT METHOD | SHOFU INC. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| US-5122061-A | Two part composition of acrylate or methacrylate monomers, trialkylboron or oxide thereof; for dental composite resin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0282280-A1 | Curable adhesive compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10149802-B2 | Filler characterized by acidic polymer treatment method | HDAC10, H1-10, CACNA1G | HCAR2 506/4885THRB 2760/4885THRA 612/4885 |
| US-20250213433-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | CDH1, MACF1, ICAM1 | HCAR2 1960/4885THRB 3873/4885THRA 2732/4885 |
| US-12527725-B2 | Solvent-free dental adhesive composition | CDH1, ITGA1, ITGB8 | HCAR2 1277/4885THRB 2741/4885THRA 2020/4885 |
| US-20210007938-A1 | LOW WATER-SENSITIVE DENTAL COMPOSITION | MGMT, DNMT3A, TAS2R1 | HCAR2 2061/4885THRB 2752/4885THRA 1318/4885 |
| US-20250064687-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | MGMT, SEM1, CARM1 | HCAR2 3757/4885THRB 2375/4885THRA 1620/4885 |
| US-20250186309-A1 | DENTAL CURABLE COMPOSITION AND DENTAL KIT | KIT, DNMT3L, CDK6 | HCAR2 4238/4885THRB 2727/4885THRA 2160/4885 |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | MSL1, ITGA1, ITGAL | HCAR2 2666/4885THRB 2959/4885THRA 1194/4885 |
| US-20160213576-A1 | FILLER CHARACTERIZED BY ACIDIC POLYMER TREATMENT METHOD | HDAC10, H1-10, CACNA1G | HCAR2 506/4885THRB 2760/4885THRA 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.