Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297076 | 1.00 | TDP1 (0.64) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL18969810 | 0.94 | TDP1 (0.72) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11985700 | 0.92 | TDP1 (0.69) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL27988563 | 0.90 | ALDH1A1 (0.69) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL10432074 | 0.90 | ALDH1A1 (0.69) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL111221 | 0.89 | LMNA (0.66) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL110817 | 0.89 | LMNA (0.66) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL5366432 | 0.89 | LMNA (0.66) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL5373212 | 0.89 | LMNA (0.66) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL5371920 | 0.89 | LMNA (0.66) | TDP1TSHRALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299004-B2 | Hydraulic fluid and hydraulic system | IDEMITSU KOSAN CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20100130394-A1 | HYDRAULIC FLUID AND HYDRAULIC SYSTEM | IDEMITSU KOSAN CO., LTD (JP) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130394-A1 | HYDRAULIC FLUID AND HYDRAULIC SYSTEM | AQP1, AQP3, TECR | TDP1 3396/4885TSHR 4028/4885ALDH1A1 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.