SCHEMBL28459505

SCHEMBL28459505

Cc1cc(Br)c(Cc2cc(C)c(C)cc2Br)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
ALOX15 P16050 2/20 0.48
CYP1A2 P05177 1/20 0.48
CASP7 P55210 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TSHR P16473 3/20 0.36
LMNA P02545 1/20 0.36
SNCA P37840 1/20 0.34
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
PTPN1 P18031 2/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15788771 0.81 TSHR (0.44) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL15788770 0.81 ALDH1A1 (0.36) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL3958466 0.79 SHBG (0.39) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL15890143 0.79 TSHR (0.36) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL24199822 0.79 SNCA (0.42) SNCACA2
SCHEMBL15701362 0.77 TSHR (0.37) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL10018125 0.75 KCNA2 (0.38) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL16425425 0.75 TSHR (0.36) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL1135594 0.75 TSHR (0.44) ALDH1A1TSHRLMNACYP3A4MAPK1
SCHEMBL29637482 0.75 TSHR (0.44) ALDH1A1TSHRLMNACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111689995-B High-solubility triaryl carbon borate and preparation method and application thereof 万华化学集团股份有限公司 2023-09-19 CN disclosed
CN-111689995-A High-solubility triaryl carbon borate and preparation method and application thereof 万华化学集团股份有限公司 2020-09-22 CN disclosed